- 期刊
Giant Juvenile Fibroadenoma in the Adolescent: Report of Two Cases
青少年型巨大乳房纖維腺瘤：兩例報告
摘要
青少年型巨大乳房纖維腺瘤並不常見，大約只佔乳房良性腫瘤的5%，她們共有的特徵常是乳房呈現無痛的腫塊，並且在短短的幾個月之內快速長大並超過5公分以上。目前對於青少年爲何會發生巨大乳房纖維腺瘤的原因還不是很清楚，一般認爲是部分乳房組織對於體內少量女性荷爾蒙過於敏感所致。由於巨大型乳房纖維腺瘤在臨床上與葉狀肉瘤不易區分，加上有惡性的可能，因此手術切除爲首選的治療方式。在此我們提出兩個病例，分別爲一個16歲及11歲的小女孩，主訴右側乳房在短短的10個月8個月之內分別長成13公分及11公分，包覆完整的腫瘤。病人接受腫瘤切除之後，病理報告證實爲青少年型巨大乳房纖維腺瘤，手術當中，乳房組織都被完整保留下來，病人於術後隔天出院，於本院追蹤10個月，無復發現象，而兩側乳房的大小也都恢復對稱。
關鍵字
無資料並列摘要
Two adolescent girls, aged 16 and 11 years respectively, each complained of unusual swelling of the right breast for 8 to 10 months. In both cases, examination revealed a diffusely enlarged right breast that was about twice as large as the left. The swelling was widespread but the breast was not tender. In both cases, a sonogram revealed a huge, well-defined tumor embedded in the lateral portion of the right breast. The overlying skin was stretched, and dilated veins could be seen on the surface. The patients were in good general health, and had regular menstrual cycles. Neither girl had a family history of breast cancer. The mass in each case was removed by wide excision, and shown by pathologic studies to be a giant juvenile fibroadenoma. We present these two cases to illustrate the principles of diagnosis and management of large breast tumors in adolescents, and to emphasize that such tumors can be removed safely, without significant damage to adjacent normal breast tissue.