- 期刊
Femur Breaking Strength and Trace Element Status of Osteoporotic Rats as Affected by Dietary Calcium and Exercise
並列摘要
The effects of dietary calcium and exercise on the femur breaking strength and trace element metabolism were investigated with the mature female ammonium chloride-induced osteoporotic rats. Sixty adult female rats were divided into five groups: one control group: adequate Ca (0.47%), non-exercise (CN) and four experi-mental groups: low Ca (0.28%), non-exercise (LN); low Ca, exercise (LE); high Ca (0.91%), non-exercise (HN); and high Ca, exercise (HE). Exercising animals ran 1 km/h (5 incline), 1 h/d, and 5 d/wk for 18 weeks. Two percent of NH4CI was added to the drinking water of the experimental groups to induce osteoporosis as shown by signifi-cantly lower femur volume in LN, LE, and HN rats, but not in HE rats, as compared with that of CN rats. Due to NH4CI ingestion, body weight loss was found in the experi-with that of CN rats. Due to NH4CI ingestion, body weight loss was found in the experi-mental groups. The femur breaking strength of the low Ca groups tended to be lower although there was no significant difference between any of the groups. Femur break-ing strength was significantly correlated with Ca intake and bone ash weight (r=0.27, P＜0.05). Plasma Fe, Zn, and Cu of the experimental groups were not affected. AI-though significant mineral interaction due to the high Ca intake was observed in bone Cu only, the bone Fe of the high Ca groups tended to be lower also. Both plasma and bone Mn were too low to be detected. Exercise had no influence on the femur breaking strength and trace element status of the osteoporotic rats. But, with the high Ca in-take, exercise could maintain the bon integrity of the osteoporotic rats.