Seizure Related to Hyponatremia in a Patient Receiving Bowel Preparation for Colonoscopy: A Case Report

Ching-Yang Chen ； Shih-Yuan Hung ； Pei-Ying Lin ； Chia-Chang Hsu

《Acta Nephrologica》 29卷2期 (2015/06) Pp. 120-123

https://doi.org/10.6221/AN.2015014

並列摘要

Hyponatremia is an under-recognized complication of bowel preparation for colonoscopy. It is usually mild and self-limited and rarely severe. To date, only a few reports have been published of marked hyponatremia with severe neurological dysfunction such as loss of consciousness and seizures. Herein, we present a case who had no previous history of seizures or hyponatremia, who developed severe hyponatremia (serum sodium 112 mEq/L) and generalized tonic seizures after receiving polyethylene glycol (PEG) for bowel preparation. The administration of concomitant thiazide was considered to be a major risk factor. We recommend withdrawing thiazide or closely monitoring the sodium level in cases of thiazide user receiving a bowel preparation, even with the relatively safe purgative regimen of PEG.

並列關鍵字

bowel preparation ； colonoscopy ； hyponatremia ； polyethylene glycol ； seizure