- 期刊
- OpenAccess
Nutritional Management of Protein-Energy Wasting in Non-Dialysis Dependent Chronic Kidney Disease: Reconciling the Dual Goals of Renoprotection and Nutritional Management
並列摘要
Low protein diet has been used to retard progression of kidney disease, and dietary protein intake of approximately 0.6 to 0.8 g/kg/day has also been shown to alleviate uremic symptoms, hyperparathyroidism, hypertension, hyperkalemia and hyperphosphatemia in addition to its renoprotective effects. Notwithstanding the various benefits of low protein diet, patients with protein energy wasting (PEW), or those at risk for protein energy wasting may require an increase in the target dietary protein intake to account for their higher protein catabolism and to aid recovery from PEW. It is currently unclear what the ideal target dietary protein intake might be in patients with kidney disease and PEW, as there is only scant clinical trial evidence to answer this question. Experts recommend a protein intake of ~ 1 g/kg/day, based on the needs of analogous patient populations such as the elderly, those with end stage renal disease, or those with acute kidney injury. Further examination of this question in controlled clinical trials will be necessary.