Gut Microbiota, Obesity and Traditional Chinese Medicine

肥胖症的患病率正在迅速地成為普遍的問題，並且在各個國家持續增加。肥胖被認為是造成代謝症候群的危險因素。腸道菌群已成為肥胖與代謝症候群疾病形成的主要因素之一。最近研究指出，利用益生菌、益菌生和抗生素可調節腸道菌群並被證實可用來治療糖尿病。傳統中草藥被認為可用來管控肥胖與代謝症候群。這篇文章描述腸道菌群與肥胖造成的發炎的機制之外，並且描述傳統中草藥對於肥胖中腸道菌群的調節。

關鍵字

腸道菌群；肥胖；內毒素（脂多醣）；腸道通透性；發炎；傳統中草藥

並列摘要

The prevalence of obesity is rapidly becoming endemic problem and continues to increase in worldwide. Obesity is proposed as risk factor of developing metabolic syndrome. The gut microbiota has emerged as an important factor in the development of obesity and metabolic syndrome. Recent studies have shown that alteration of the gut microbiota is associated with an obese phenotype. The protective effect against diabetes of gut microbiota modulation with prebiotic, probiotics or antibiotics has been confirmed in recent observations. Traditional Chinese medicine (TCM) is an excellent alternative and complementary medicine for management of obesity and metabolic syndrome. In this review, we describe the relationship between the gut microbiota and obesity, and the mechanisms by which the gut microbiota influence inflammation in obesity. We then described the potential role of TCM in mediating the effects of the gut microbiota in the development of obesity.

並列關鍵字

gut microbiota ； Obesity ； LPS ； Metabolic endotoxemia ； Gut permeability ； Inflammation ； Traditional Chinese Medicine

國際替代計量

Gut Microbiota, Obesity and Traditional Chinese Medicine

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