- 期刊
Menetrier's Disease Associated with Giant Gastric Adenoma and Helicobacter Pylori Infection
Menetrier氏症合併巨大胃腺瘤及幽門螺旋桿菌感染
摘要
Menetrier氏症是少見的疾病，迄今原因不明。我們報告一個罕見的Menetrier氏症患者併發一個巨大的胃線瘤。此62歲之家庭主婦因上腹痛及食慾不振來本院求診，上消化道內視鏡檢查發現整個胃的皺摺均變粗，而且在胃竇部有一個巨大的息肉狀腫塊，經切片證實爲管狀併絨毛狀之胃腺瘤。病患接受全胃切除術，病理檢查證實爲廣泛型Menetrier氏症、胃線瘤、並有幽門螺旋桿菌感染，手術後病患恢復良好，血紅素及血清白蛋白數值均回升。此病例暗示Menetrier氏症、胃腺瘤和幽門螺旋桿菌似乎有某些關聯，三者的關係値得進一步研究探討。全胃切除術可以治癒此種廣泛型Menetrier氏症併胃腺瘤。
並列摘要
Menetrier's disease is a rare disease of unknown etiology. We described the first report of the coexistence of Menetrier's disease and gastric adenoma. The 62-year-old Chinese woman presented with epigastric pain and anorexia. Upper gastrointestinal endoscopy demonstrated enlarged folds in entire stomach and a giant polypoid mass in the antrum. Gastric biopsies revealed that the mass lesion was a tubulovillous adenoma. She subsequently underwent a total gastrectomy. Histological examination of the resected stomach confirmed the diagnosis of adenoma and demonstrated diffuse form of Menetrier's disease with H. pylon infection. The patient recovered well after surgery. This case suggests a link among gastric adenoma, Menetrier's disease and H. pylon infection. Elective total gastrectomy can cure the diffuse form of Menetrier's disease associated with gastric adenoma.