Prevalence and Associated Factors of Hyperechoic Pancreas on Sonography

高超音波回音胰的盛行率及其相關因子

梁志明(Chih-Ming Liang) ； 吳耿良(Keng-Liang Wu) ； 周業彬(Yueh-Pin Chou) ； 戴維震(Wei-Chen Tai) ； 邱逸群(Yi-Chun Chiu) ； 張簡吉幸(Chi-Sin Changchien) ； 邱世賢(Shue-Shian Chiou) ； 胡琮輝(Tsung-Hui Hu) ； 蔡成枝(Seng-Kee Chuah)

《臺灣消化醫學雜誌》 28卷3期 (2011/09) Pp. 11-18

https://doi.org/10.6557/GJT.201109_28(3).0002

摘要

背景：高超音波回音肝臟被認爲是脂肪肝已有許多研究證實，但高超音波回音胰卻很少被研究。本研究目的是爲了了解高超音波回音胰的盛行率與相關因子。方法：回溯性分析本院96年3月至97年6月共600人次健檢中心資料，剔除影像不良的影像資料，共353人的資料收入研究中。高超音波回音胰的定義是和後腹腔脂肪超波做比較，若比後腹腔脂肪超音波回音相當或略低者爲高超音波回音胰，反之則否。比較高超音波回音胰與性別、年齡、身體質量指數、腹圍、血壓、血脂肪、血糖、尿酸、腎臟功能、電解質的相關性。分析高超音波回音胰與代謝性症候群、脂肪肝、膽結石和膽息肉之相關性。結果：在單變項分析，高超音波回音胰與男性、身體質量指數、腹圍、血壓、血脂肪、尿酸、血糖有顯著相關。在多變項分析，男性、腹圍（男性≥90 cm，女性≥80cm）、總膽固醇(≥200 mg/dL)爲獨立相關因子，勝算比(Odds Ratio)分別爲 2.22, 2.82, 1.87.高超音波回音胰亦與代謝性症候群、脂肪肝有正相關。結論：高超音波回音胰與男性、腹圍、高血脂及其他代謝性症候群的因子有相關性，所以高超音波回音胰也許可當成脂肪胰。但仍需要更多研究來佐證。

關鍵字

高超音波回音胰 ； 後腹腔脂肪 ； 代謝性症候群 ； 脂肪肝

並列摘要

Background and Aims: In the liver, diffuse hyperechoic regions usually represent fat deposits. Hyperechoic or bright regions in the pancreas, however, are not well studied. We investigated the clinical implications of hyperechoic pancreas to understand the prevalence and associated factors of this finding.Materials and Methods: A total of 353 sonograms of the pancreas of subjects who underwent a comprehensive health examination in a medical center were reviewed and included in the current analysis. Metabolic syndrome criteria from the National Cholesterol Education Program Adult Treatment Panel III (ATP III in the Asia-Pacific Region) were applied. Hyperechoic pancreas was defined as a homogeneous echogenicity of the pancreatic body that was slightly lower than or equal to the echogenicity of retroperitoneal fat.Results: Sonographically hyperechoic pancreas was significantly associated with male gender (odds ratio OR, 2.22; 95% confidence interval CI, 1.34-3.68), waist circumference (male ≥ 90 cm, female ≥ 80 cm; OR, 2.82; 95% CI, 1.53-5.20), and total cholesterol (≥ 200 mg/dL; OR, 1.87; 95% CI, 1.15-3.03). Hyperechoic pancreas was correlated with fatty liver. The incidence of metabolic syndrome was higher in the hyperechoic pancreas group.Conclusions: The prevalence of sonographically hyperechoic regions in the pancreas was associated with greater waist circumference and other types of hyperlipidemia. Sonographically hyperechoic pancreas showed a strong correlation with fatty liver and metabolic syndrome. Therefore, sonographically hyperechoic pancreas may indicate the presence of ”fatty pancreas”.

並列關鍵字

sonographically hyperechoic pancreas ； retroperitoneal fat ； metabolic syndrome ； fatty liver