Heterocycles with Built-in Pseudothiourea Pharmacophores 2. Synthesis and Biological Activities of Thiazole-and [1,3] Thiazine-fused Benzimidazoles, Quinazolines and Perimidines

徐令儀(Ling-Yih Hsu) ； 胡明寬(Ming-Kuan Hu) ； 劉剛劍(Kang-Chien Liu)

《The Chinese Pharmaceutical Journal》 55卷3期 (2003/06) Pp. 153-168

https://doi.org/10.7019/CPJ.200306.0153

並列摘要

The present review covers forty-three scientific papers, most from our laboratory, which deal with the synthesis and biological evaluation of a series of condensed benzimidazoles, quinazolines and perimidines. These compounds, containing pseudothiourea as a general structural unit, exhibited considerable biological activities, such as antihypertensive, diuretic anorectic, and thermoregulating effects on animals as well as good herbicidal properties against hydroponieally grown greens.

並列關鍵字

Thiazolo[3,2-a]benzimidazoles ； [1,3]Thiazino[3,2-a]benzimidazoles ； Thiazolo[2,3-b]quinazolines ； [1,3]Thiazino[2,3-b]quinazolines ； Thiazolo[3,2-a]perimidines ； [1,3]Thiazino[3,2-a]perimidines ； Antihypertensiv