The existence of high-rise buildings can cause acceleration of near-ground wind and changes the local pedestrian wind environment, leading to influence of pedestrian comfortability and even human safety. Therefore, it is necessary to assess the pedestrian wind environment at the design stage of high-rise buildings. In the study, CFD was adopted to simulate pedestrian wind flows in two urban areas and the predictions were compared with the wind tunnel experiment results. The reliability of the CFD predictions of urban pedestrian wind was further assessed according to foreigner related studies and simulation criteria. It was found that although some the predictions were underestimated, the results were in reasonable linear correlation with the experimental data. After appropriate corrections and introduce the reasonable pedestrian wind comfort assessment criteria, it is expected that numerical simulation would become a good tool to assess the pedestrian wind environment.