研究目的:要分析攝護腺結石的成分,其形成與血中攝護腺特異指數,攝護腺切下來的重量及尿液白血球數目的關係。並且分析其形成與連路結石的相關事宜。 材料與方法:我們從三十一位病患因攝護腺肥大接受經尿道攝護腺切除手術後取得的攝護腺結石送去分析其成份。我們用統計計算法分析攝護腺特異數、攝護腺切下來的重量、及尿液白血球數目的床意義。我們用靜脈泌尿道攝影報告、泌尿道的超音波報告及肺胱尿道鏡的發現來分析尿路結石的相關事宜。 結果:內源性衍生而成的攝護腺結石佔所有攝護腺結石的32.2%。外源性衍生而成的攝護腺結石佔所有攝護腺結石的16.1%。有一半的攝護腺結石(51.6%)為磷酸鈣及草酸鈣的混合。少部分的攝護腺結石病患(9.6%-19.3%)以前有尿路結石。隨著攝腺切除重量的增加,其結石的成也會增多。血清的攝護腺特異指數與攝護腺結石無關係,尿液的白血球數目與攝護腺結石引發的攝護腺炎無關係。 結論:台北榮民總醫院的攝護腺結石有一半(51.6%)是混合成份衍生而成。隨著攝護腺切除重量的增加,其結石的成也會增多。血清的攝護腺特異指數及尿液中的白血球數目與攝護腺結石發炎無關係,少部分的攝護腺結石病患(9.6%-19.3%)以前有尿路結石的病史。
OBJECTIVE: To analyze the composition of prostatic calculi, and their association with serum prostate-specific antigen (PSA) level, weight of the resected prostatic adenoma, urine white blood cell (WBC) count, and urinary tract calculus formation. MATERIALS AND METHODS: We analyzed the compositions of prostatic calculi retrieved from 31 consecutive patients after transurethral resection of the prostate using infrared spectroscopy. We used non-parametric and Fischer’s exact test to analyze their association with serum PSA level, resected weight of the prostatic adenoma, and urine WBC count. We used intravenous urography (IVU) reports. Urinary tract sonography reports, and cystourethroscopic findings to analyze their association with urinary tract calculus formation. RESULTS: Endogenous prostatic calculi comprised 32.2% while exogenous prostatic calculi comprised 16.1% of all calculi analyzed. Half of the prostatic calculi (51.6%) were a combination of calcium phosphate and calcium oxalate. A proportion of patients with prostatic calculi (9.6%-19.3%) had previous urinary tract calculi. Increasing the weight of the resected prostatic adenomas was associated with more than 1 composition of prostatic calculi. Serum PSA level and urine WBC counts were not associated with prostatic calculus formation or calculus-induced prostatitis. CONCLUSIONS: Nearly 1/3 of prostatic calculi (32.2%) at Taipei Veterans General Hospital were endogenous in origin. About 1/6 of prostatic calculi (16.1%) were exogenous in origin. Half of these calculi (51.6%) had a mixed composition. A proportion of patients with prostatic calculi (9.6%-19.3%) had previous urinary tract calculi. Increasing the weight of the resected prostatic adenomas was associated with more than 1 compostatic of prostatic calculi. Serum PSA and urine WBC counts were not associated with prostatic calculus formation or prostatitis.