持續性的肝炎,造成進行性的肝纖維化,最終形成肝硬化。本文在整理肝硬化臨床的診斷與治療。病因與危險因子:在台灣病毒性肝炎是傳統上造成肝硬化原因的大宗,惟酒精性肝炎和脂肪肝在近期有增加的趨勢。診斷:肝臟生檢仍是診斷肝硬化的黃金準則,但臨床上輔以病史、理學檢查、血液血清檢驗,以及影像診斷,仍可提供肝硬化的線索。治療:治療肝硬化病人的核心目標在於預防及治療併發症,以延緩肝臟疾病的惡化;當疾病進展到末期肝病的時期,唯一的治療,就只有換肝一途。
Persisted hepatitis causes progressive liver fibrosis and leads to liver cirrhosis. And this article is to provide clinical information about diagnosis and treatment for liver cirrhosis. Etiology and Risk Factors: Viral hepatitis contributed to most of liver cirrhosis cases in Taiwan. However, alcoholic liver disease and fatty liver are in increasing in these days. Diagnosis: Liver biopsy is the golden standard of diagnosis of liver cirrhosis. History taking, physical examination, lab data, and image studies may provide clues of liver cirrhosis clinically. Treatment: The goal in treating liver cirrhosis is to prevent and to manage the complication. When the disease merging into end stage liver disease, the only treatment is liver transplantation.