肢端肥大症之診治：台灣專家共識

Expert's Consensus on Management of Acromegaly in Taiwan

張天鈞(Tien-Chun Chang)

《內科學誌》 27卷6期 (2016/12) Pp. 283-294

https://doi.org/10.6314/JIMT.2016.27(6).01

摘要

肢端肥大症乃因青春期後患者的生長素和似胰島素生長因子-1分泌過多，進而導致全身組織器官不正常的增生或肥大，包括外表改變等多種病理變化的慢性內分泌疾病。主要是因腦下垂體生長素瘤所致。盛行率約為每百萬人40-125例，每年新增約3-4例／每百萬人。本共識乃由國內這方面之專家開會數次達成之共識，就其診斷、治療和追蹤提出大致之見解，供大家做為這個疾病診治上之參考。

關鍵字

肢端肥大症(Acromegaly) ； 診斷(Diagnosis) ； 治療(Treatment) ； 追蹤(Follow-up) ； 共識(Consensus)

並列摘要

Acromegaly is due to overproduction of GH and insulin-like growth factor-1 after puberty, which resulting in abnormal hyperplasia or hypertrophy of generalized organs. These include appearance and other pathological changes. It is a chronic endocrine disorder. The major cause is growth hormone producing tumor of the pituitary gland. The prevalence rate is 40-125/1,000,000. Annual increase of 3-4 cases/1,000,000. This consensus of diagnosis, treatment and follow-up of acromegaly is formed after several meetings of specialists in this field in Taiwan, to provide for the reference of management of this disorder.