In transportation activities, providing a workload balance for drivers and vehicles can contribute several benefits for the firm. However, few attention has been paid to the importance of workload balance in location-routing problem (LRP) research. Thus, this study intends to present a mathematical model to solve the multi-objective LRP which addresses this issue. The proposed model considers two objective functions: (1) to minimize the total cost and (2) to balance the workload in distribution activities. The main purposes of this model are to obtain the optimal location of a distribution center, number of vehicles established, and delivery routes which satisfy both of these two objectives. Furthermore, to solve the model, this study proposes the non-dominated sorting genetic algorithm-II (NSGA-II) for several problem scenarios with different numbers of customers. The experimental results show that the proposed algorithm performs well in terms of quality and computational time of the solution.