肋膜間皮瘤是一種少見的腫瘤,起源於肋膜之臟層或壁層,其致病機轉至今尚不明瞭。瀰蔓型惡性間皮瘤常與石棉之接觸暴露有關係,局限型間皮瘤則與石棉很少有關連。一般所見良性間皮瘤病例多呈弧立性,邊緣平整或有被膜之腫塊。大部份文獻報告的孤立性肋膜間皮瘤是纖維型的,僅少數為表皮細胞型。最近榮總發見兩例局限纖維型的肋膜間皮瘤:一例起自肋膜壁層,另一例則起自臟層且有柄蒂相連接。有關兩例的臨床表徵與胸部X光所見提出報告,以供參考。兩例腫瘤皆經胸腔外科手術完全割除,其中一例雖然腫塊較大與右下肺葉粘連且緊密的附著於模膈膜上。局限型良性間皮瘤經外科手術完全切除之治療,其效果於文獻的報告很好。
Mesothelioma is a rare tumor, it may arise from either parietal or visceral pleura. Localized benign mesotheliomas are usually solitary, circumscribed or encapsulated masses. Most of cases of solitary benign mesotheliomas reported in the literature are exclusively fibrous. Recently, we found 2 cases of this sort of tumor, one was originated from parietal pleura and the other from visceral pleura which was attached on a narrow pedicle. Clinical features and chest radiographic findings in both cases are described and the literatures about this disease are reviewed. Tumors of both cases were completely excised at thoracotomy though there was certain adhesion with right lower lobe and the right dome of diaphragm in case 2. A complete surgical resection can adequately treat the cases of local benign pleural mesothelioma.