Caffey's Disease (Infantile Cortical Hyperostosis)

Caffey氏病（嬰兒骨皮質增生症）

施焄鏻(Shin-Lin Shih) ； 黃倫奕(Lun-Yick Wong)

《中華放射線醫學雜誌》 11卷3期 (1986/09) Pp. 251-255

摘要

馬偕醫院最近三年以來，共有三個Caffey氏病（嬰兒骨皮質增生症）病人，其平均發作年齡是10週，其中兩位是女嬰，一位男嬰。這些病人皆呈現躁動不安、皮下組織腫脹和骨皮質增厚；其中一位病人合併發燒。實驗室檢查，顯示白血球、血小板增多，同時有鹼性磷酸酶上升，其中兩位有紅血球沈澱率上升。兩位病人呈下頜骨病變，另外一位病人則是銷骨病變。所有病人都接受indomethacin治療，療效不錯。

並列摘要

These are three cases of Caffey's disease in the Mackay Memorial Hospital for the recent 3 years. The average age at onset is about 10wks. The incidence in male and female is one to two. All the three patients were presented with irritability, swelling of soft tissue and cortical thickening of the underlying bones. One of these patients was associated with fever. The laboratory findings showed leukocytosis, thrombocytosis, increased alkaline phosphatase activity of blood serum. Two of them revealed increased sedimentation rate of erythrocyte. The radiographic features show mandibular bone involvement of two patients and clavicular bone of one patient. All the patients were given indomethacin. The clinical course was smooth.