長庚紀念醫院在1985至1988年間,共6例胰島瘤(insulinoma)實施經皮穿肝胰靜脈血取樣的方法(percutaneous transhepatic pancreatic venous sampling)來測定門靜脈系統內不同部位的胰島素的濃度,這6例病灶雖然經過超音波、電腦斷層攝影及血管攝影診斷為正常胰臟,但經胰靜脈血取樣其放射免疫性胰島素濃度卻有顯著升高的現象。利用此法其中5例找到了胰島瘤的正確位置,這種技術是隱發胰島瘤(occult insulinoma)重要定位方法。
Insulin concentrations in the portal venous system of 6 patients with insulinoma were measured using a percutaneous transhepatic method in Chung Gung Memorial Hospital from 1985 to 1988. All six cases showed mi-diagnostic ultra-sound, computed tomography and angiographic studies. These patients, however, had an increased level of radio-immunoactive insulin concentration (IRI) in the portal venous system. The tumor sites were accurately located in 5 cases by measuring radio-immunoactive insulin concentrations with percutaneous transhepatic pancreatic venous sampling (THPS) used. No complications were experienced, indicating that this method is safe and may play an important role in the localization of occult insulinoma.