摘要
50名患有小於5cm的肝細胞癌的病人，經過3年以上的追踪，發現在亞臨床期沒有症狀的肝細胞癌病人群的1、2、3年存活率分別為92.9%，85.7%，78.6%，有症狀群的存活率為80.8%，61.5%，30.8%。16位病人(32%)血清AFP值低於20ng/ml，18人(36%)介於200ng/ml與200ng/ml之間，16人(32%)高於200ng/ml。AFP值與腫瘤大小沒有平行關係。50位病人都有超音波、電腦斷層和血管攝影檢查，它們對小型肝細胞癌之預期偵察率分別為81%，77%，86%。小於2cm的肝細胞癌有76.5%屬低回音性病灶，3cm以上者84.6%為高回音性病灶。電腦斷層攝影對直徑2cm以下的肝細胞癌偵察力較差，小於1cm者幾乎沒辦法確認出來。這項資料顯示血管攝影檢查仍是最敏感、最具特異性的檢查。預料腫瘤可以切除者，在做完血管攝影之後，由肝動脈注入2-3ml油性碘劑，2星期後再做電腦斷層攝影，當有助於提高癌症分期之正確性。
並列摘要
Fifty patients with hepatocellular carcinoma (HCC) of small size (less than 5 cm in diameter) were revealed and analyzed. The 1,2, and 3-year survival rates were 92.9%, 85.7%, 78.6% for the asymptomatic patients and 80.8%, 61.5%, 30.8% for the symptomatic patients. The level of AFP was normal in 16 patients (32%), raised to 20-200 ng/ml in 18 patients (36%) and was higher than 200 ng/ml in the remaining 16 patients (32%). The level of AFP was not paralleled with the tumor size. Ultrasound (US), computed tomogram (CT) and angiogram (A) were available for all patients. Predictive accuracy of US, CT and A in diagnosis of small HCC was 81%, 77%, 86% respectively. The US echo-pattern was non-specific. Hypoechoic pattern in HCC was found in 76.5% of HCC less than 2 cm in size while 84.6% were hyperechoic or mixed echo pattern larger than 3 cm in size. Computed tomography was less sensitive for detecting HCC smaller than 2 cm in size. It was almost impossible to diagnose a lesion ＜1 cm by CT. According to this sudy, angiography was proved to be more informative than CT and US. For the resectable HCC, Lipoidol-CT might be valuable in tumor staging.