- 期刊
- OpenAccess
正常中國人之豆核大小
Size of Lentiform Nuclei in Normal Chinese
摘要
The size of lentiform nuclei is not only very important for stereotactic neuronal transplantation and pallidotomy, but is also one of the criteria of disease diagnosis. We reported on 100 patients evenly distributed by age (about 10 patients in each 10-year range) with equal sex distribution. All had a normal brain CT. We calculated the maximal length and width of lentiform nuclei at the level of the anterior commissure-posterior commissure (AC-PC) line. In addition, the width of the third ventricle and the distance from the midline to the innermost point of the lentiform nuclei were also measured. The mean values were LLNW (left lentiform nuclear width) 18.23mm, LLNL (left lentiform nuclear length) 34.61mm, RLNW (right lentiform nuclear width) 34.47mm, RLNL (right lentiform nuclear length, TVW (third ventricular width) 5.57mm, MLLN (midline to left lentiform nuclear inner margin) 11.34mm, and MRLN (midline to right lentiform nuclear inner margin) 11.31mm. A t-test showed significant differences between men and women in TVW, MLLN and MRLN. If MLLN and MRLN minus TVW, there were no significant differences between sexes. There were no significant sex differences between MRLN, MLLN and TVW. We think the difference in TVW between sexes may be due to the age difference, because the average age of the men was 47 and the women 42. MRLN, MLLN and TVW had a positive correlation with age (p＜0.02), while LLNW and RLNW had a negative correlation (p＜0.02). The length of the lentiform nuclei had no significant correlation with age. The MRLN and MLLN had a positive correlation with TVW (p＜0.02), while the LLNW and RLNW had negative correlations. In healthy Chinese, we found the lentiform nuclei shrink with age, and the width of the third ventricle and the distance between the AC-PC line to the inner lentiform nuclear border grow with age. These findings are important for stereotactic pallidotomy, because in the past, the Talairach scalar system was used without any adjustment for the patient’s age or individual differences. In addition, there may be changes in patients with basal ganglia disease. Therefore, surgical results may vary and result in complications if normal variations are not considered. For this reason, we recommended using an anatomical image, such as MRI, to determine a stereotactic target point, in addition to the Talairach frame only.
並列摘要
The size of lentiform nuclei is not only very important for stereotactic neuronal transplantation and pallidotomy, but is also one of the criteria of disease diagnosis. We reported on 100 patients evenly distributed by age (about 10 patients in each 10-year range) with equal sex distribution. All had a normal brain CT. We calculated the maximal length and width of lentiform nuclei at the level of the anterior commissure-posterior commissure (AC-PC) line. In addition, the width of the third ventricle and the distance from the midline to the innermost point of the lentiform nuclei were also measured. The mean values were LLNW (left lentiform nuclear width) 18.23mm, LLNL (left lentiform nuclear length) 34.61mm, RLNW (right lentiform nuclear width) 34.47mm, RLNL (right lentiform nuclear length, TVW (third ventricular width) 5.57mm, MLLN (midline to left lentiform nuclear inner margin) 11.34mm, and MRLN (midline to right lentiform nuclear inner margin) 11.31mm. A t-test showed significant differences between men and women in TVW, MLLN and MRLN. If MLLN and MRLN minus TVW, there were no significant differences between sexes. There were no significant sex differences between MRLN, MLLN and TVW. We think the difference in TVW between sexes may be due to the age difference, because the average age of the men was 47 and the women 42. MRLN, MLLN and TVW had a positive correlation with age (p＜0.02), while LLNW and RLNW had a negative correlation (p＜0.02). The length of the lentiform nuclei had no significant correlation with age. The MRLN and MLLN had a positive correlation with TVW (p＜0.02), while the LLNW and RLNW had negative correlations. In healthy Chinese, we found the lentiform nuclei shrink with age, and the width of the third ventricle and the distance between the AC-PC line to the inner lentiform nuclear border grow with age. These findings are important for stereotactic pallidotomy, because in the past, the Talairach scalar system was used without any adjustment for the patient’s age or individual differences. In addition, there may be changes in patients with basal ganglia disease. Therefore, surgical results may vary and result in complications if normal variations are not considered. For this reason, we recommended using an anatomical image, such as MRI, to determine a stereotactic target point, in addition to the Talairach frame only.