The Hawkins sign was thought to be useful as an early negative predictor of avascular necrosis (AVN) following a fracture through the talar neck. It had not, however, been applied to fractures through the femoral neck. We evaluated the applicability of the Hawkins sign for fractures through the femoral neck, and compared with those through the talus. Radiographs of 10 ankles with fracture of the talus and 12 hips with fracture of the femoral neck in our hospital were reviewed retrospectively. In 6 of the ankles, the Hawkins sign was positive without evidence of AVN on serial follow-up radiographs. The rest of the ankles in which the Hawkins sign was absent eventually developed AVN. In contrast, none of the hips showed a positive Hawkins sign, but AVN was noted in only 2 cases. We concluded that the Hawkins sign is useful for prediction of the blood-supply status of the talar body, but not for the femoral head. The cause of this discrepancy between the talus and the femur is unknown. Different areas of weight-bearing may be a possible factor. A further study with a large number of cases and with long-term longitudinal radiographic follow-up is necessary.