Prepyloric antral webs are relatively uncommon as a cause for gastrointestinal obstruction in infants and children. Many synonyms exist for this entity, including antral mucosal diaphragm, prepyloric septum, gastric antral diaphragm, antal membrane, and prepyloric antral membrane. We recently encountered two cases of prepyloric antral webs in neonates less than 5 days old.