- 期刊
- OpenAccess
Fluid-attenuated Inversion Recovery Magnetic Resonance Images in Children with Intracranial Inflammatory Disease
兒童顱內發炎病灶之磁振液體訊號減弱之反轉回復影像
摘要
為了評估FLAIR波序偵測顱內發炎病灶的效用並增進此類病灶的偵測，本研究於最近三年之內施用FLAIR影像、快速自旋T2影像與打完顯影劑(Gd-DTPA) T1W影像於三十六位罹患顱內發炎病症的兒童並加以比較。此研究發現，FLAIR影像在偵測顱內發炎病灶明顯比T2W影像好，尤其是位於腦部周圍的病灶。而化膿性腦膜炎病灶，只有FLAIR影像及打完顯影劑(Gd-DTPA) T1W影像可見，快速自旋T2影像則幾乎正常。這是由於FLAIR波序能有效抑制蜘蛛膜下腔內腦脊髓液的訊號，又能顯出病變的T2延長現象。然而打葯以後的T1自旋影像對於偵測軟腦膜病變仍然很重要。因此建議可將FLAIR波序包括在顱內發炎病患的磁振掃描常規檢查之中。
並列摘要
For the purpose of evaluating the efficacy of the fluid-attenuated inversion recovery (FLAIR) pulse sequence and increasing the sensitivity of detecting inflammatory lesions in children, we compared FLAIR with fast T2-weighted images in 36 patients who had intracranial inflammatory diseases in the last 3 years. Our results disclosed that FLAIR images detected significantly more lesions than did fast T2-WI (p＜0.01) and contrast-enhanced T1-Weighted images. The FLAIR pulse sequence combined with T2-weighting with nulling of the signal from cerebrospinal fluid was superior to fast spin-echo sequences in detecting peripheral and periventricular lesions. Post-contrast-enhanced T1-weighted images were more suitable for detecting leptomeningeal processes than were FLAIR images. We conclude that FLAIR images are complementary to fast T2-weighted images and contrast-enhanced T1W images. We suggest that FLAIR should be part of routine brain MR imaging protocols, particularly to define parenchymal lesions adjacent to the ventricles and sulci.