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Comparison of Breath-Holding Turbo Spin Echo and Expiratory-Triggered HASTE Sequences for Resovist-Enhanced MR Imaging of Liver Lesions
注射Resovist之肝臟腫瘤磁振影像在閉氣性TSE與呼吸驅動HASTE臨床診斷效果之比較
摘要
快速T2WI磁振造影技術是偵測肝臟局部腫瘤必備的重要技術。在本文中，主要是比較2種快速T2WI磁振造影技術（閉氣性TSE及呼吸驅動HASTE）在注射Resovist顯影劑後之肝臟腫瘤的偵測能力。共收集13個病人之21個腫瘤，進行顯影劑前後定性及定量的分析。在初步結果中，注射顯影劑前，閉氣性TSE有較高影像品質；但在注射顯影劑後，閉氣性TSE有比較高的PSIL，閉氣性TSE和呼吸驅動HASTE在影像品質方面並沒有太大的差別。在另一方面，呼吸驅動HASTE比較沒有移動性假影，而且在測量 PSIL時比較可信賴；而且呼吸驅動HASTE有比較高的SNR；針對惡性腫瘤中，呼吸驅動HASTE也有比較高的CNR。本研究結果發現，在注射Resovist顯影劑後，呼吸驅動HASTE比閉氣性TSE有相同或更好的臨床診斷效果。
並列摘要
Fast imaging techniques are essential for acquiring T2WI with good quality for diagnosis of focal liver lesions. The purpose of our study was to compare the diagnostic performance of two fast T2-weighted imaging sequences, breath-holding turbo spin-echo (BH-TSE) and expiratory-triggered half-Fourier single-shot spin-echo (ET-HASTE), on liver MR imaging with a superparamagnetic iron oxide (SPIO) liver-specific contrast agent (Resovist). Qualitative and quantitative analyses of twenty one focal liver lesions from thirteen patients were studied before and after Resovist administration. The preliminary results revealed that better image quality of BH-TSE sequence was obtained before Resovist administration. There was a higher percentage of signal-intensity loss (PSIL) of BH-TSE sequence, but no significant difference in image quality between BH-TSE and ET-HASTE sequences after Resovist administration. On the other hand, ET-HASTE sequence was superior to BH-TSE sequence in free of motion artifacts, and had a higher lesion signal-to-noise ratio (SNR) for all lesions, higher lesion-to-liver contrast-to-noise ratio (CNR) for malignant lesions, as well as a more reliable PSIL measurement. In conclusion, the ETHASTE was comparable with or better than the BH-TSE sequence in Resovist-enhanced liver MRI.