跟骨定量超音波儀應用於健康篩檢之適當性評估

Evaluation of the Application of Quantitative Ultrasound of the Calcaneus in Health Examination

羅煥鉅(Huan-Chu Lo) ； 王梅芳(Mei-Fang Wang) ； 黃立宗(Li-Chung Hwang) ； 郭俞良(Yu-Liang Kuo)

《中華放射線醫學雜誌》 Volume 30 Issue 4 (2005/08) Pp. 213-216

Abstracts

The aim of our study was to evaluate the difference and agreement between quantitative ultrasound (QUS) and dual X-ray absorptiometry (DXA) using statistical method, which is suitable for the health examination.
Ninety-eight consecutive patients (female, 49±12 years old) of perimenopause were examined in this study. DXA of the lumbar spine was performed to acquire the BMD values and were expressed as T-score. At the same session, the calcaneus of the same patients was examined with QUS. Paired T-test and linear regression were performed to observe the relationship between QUS and DXA. The level of agreement was analyzed with weighted kappa (wk) statistics.
The paired T-test for comparison of T-score of DXA and QUS showed t-value about 5.943 (P＜0.001), which was statistical significance. Pearson's correlation coefficient for the comparison of QUS with DXA was R=0.714 (P＜0.0001). Using single proportion test, the diagnostic percentage of osteoporosis was also significant difference (significant statistic) of between the DXA (11.2%) and QUS (20.4%) (Z=2.135, 0.028＜P＜0.03). By weighted kappa statistic of T-score, the diagnostic disagreement was found between QUS and DXA, the agreement was fair (kappa score =0.258, P＜0.0001).
QUS cannot replace DXA; it may be an alternative method for high-throughput screening tool for osteoporosis in health examination if it had been standardized as DXA. QUS is not recommended for diagnosis and monitoring of osteoporosis.

Keywords

雙能X光骨密度儀 ； 骨質疏鬆 ； 定量超音波儀 ； 跟骨

Parallel abstracts

The aim of our study was to evaluate the difference and agreement between quantitative ultrasound (QUS) and dual X-ray absorptiometry (DXA) using statistical method, which is suitable for the health examination.
Ninety-eight consecutive patients (female, 49±12 years old) of perimenopause were examined in this study. DXA of the lumbar spine was performed to acquire the BMD values and were expressed as T-score. At the same session, the calcaneus of the same patients was examined with QUS. Paired T-test and linear regression were performed to observe the relationship between QUS and DXA. The level of agreement was analyzed with weighted kappa (wk) statistics.
The paired T-test for comparison of T-score of DXA and QUS showed t-value about 5.943 (P＜0.001), which was statistical significance. Pearson's correlation coefficient for the comparison of QUS with DXA was R=0.714 (P＜0.0001). Using single proportion test, the diagnostic percentage of osteoporosis was also significant difference (significant statistic) of between the DXA (11.2%) and QUS (20.4%) (Z=2.135, 0.028＜P＜0.03). By weighted kappa statistic of T-score, the diagnostic disagreement was found between QUS and DXA, the agreement was fair (kappa score =0.258, P＜0.0001).
QUS cannot replace DXA; it may be an alternative method for high-throughput screening tool for osteoporosis in health examination if it had been standardized as DXA. QUS is not recommended for diagnosis and monitoring of osteoporosis.

Parallel keywords

Dual X-ray absorptiometry ； Osteoporosis ； Quantitative ultrasound ； Calcaneus