採EMA/CO藥方治療絨毛膜癌失敗後的救援治療

The Salvage of high-risk Gestational Trophoblastic Neoplasia Patients after EMA/CO Regimen Failure

李耀泰(Yiu-Tai Li) ； 陳福民(Fu-Min Chen) ； 關龍錦(Long-Ching Kuan) ； 翁紹評(Shao-Ping Weng) ； 郭宗正(Tsung-Cheng Kuo)

《中華民國婦癌醫學雜誌》 2005年2期 (2005/10) Pp. 7-13

https://doi.org/10.7010/JGO.200510.0007

並列摘要

The regimen of choice for patients with high-risk gestational trophoblastic disease is etoposide/methotrexate/actinomycin D/cyclophosphamide/vincristine(EMA/CO). However, approximately 20-30% of patients develop resistance to EMA/CO regimen. When the EMA/CO treatment failed, it should be considered to use the combination of invasive surgery, radiotherapy and novel chemotherapeutic agents. Salvage drugs reported include cisplatin, paclitaxel, ifosfamide, carboplatin, 5-fluorouracil, bleomycin and adriamycin. There still present the substantial possibility of complete remission even in those who present with advanced stage of disease.

並列關鍵字

gestational trophoblastic disease ； chemotherapy ； radiotherapy ； surgery