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過敏性鼻炎的診斷性檢查

Diagnostic Test of Allergic Rhinitis

摘要


診斷過敏性鼻炎的三大要素:過敏性鼻炎症狀、理學檢查及實驗室檢驗。包含過敏症狀、家庭史、生活環境及治療史的問診,是診斷與治療過敏性鼻炎最重要的一環。然而要確定診斷,需要實驗室檢驗才有辦法分辨出過敏性鼻炎、局部過敏性鼻炎與非過敏性鼻炎。過敏性鼻炎檢驗的第一線工具為皮膚挑刺試驗及血清特異性IgE檢驗,前者在台灣臨床上已經如同皮下減敏治療一樣,消失多年了。後者常見的為定性篩檢用的phadiotop,半定量的MAST(multiple antigen simultaneous test)與ISAC(immuoCAP solid-phase allergen chip),以及定量的CAP檢驗。鼻腔過敏原誘發試驗是驗證過敏性鼻炎的黃金標準,也是診斷局部過敏性鼻炎的方法之一。同樣因為耗時與需求量少,也不見於台灣實際臨床運用了。

並列摘要


Allergic rhinitis is diagnosed based on the following: symptoms of allergic rhinitis, physical examinations, and laboratory examinations. History taking, including symptoms, family history, environment, and treatment history, is the most important factor in the diagnosis and treatment of allergic rhinitis. However, to confirm an exact diagnosis, laboratory data are needed to differentiate between allergic rhinitis, local allergic rhinitis, and non-allergic rhinitis. The first-line tools used to test for allergic rhinitis are the skin prick test and the serum antigen-specific immunoglobulin E test. The former has disappeared from Taiwan for years as a subcutaneous immunotherapy. The latter includes the qualitative Phadiatop test, the semi-quantitative multiple antigen simultaneous test (MAST), the immunoCAP solid-phase allergen chip test (ISAC), and the quantitative CAP test. The nasal provocation test is the gold standard for diagnosing allergic rhinitis. It is also used to confirm the presence of local allergic rhinitis. However, it is not used in clinical practice in Taiwan because it is time-consuming and has few requirements.

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