主唾液腺主要可分為3大腺體,如腮腺、下頷腺及舌下腺,其功能為製造及分泌唾液,倘若發生阻塞時,便會產生腫脹或疼痛等症狀。而唾液腺結石是唾液腺最常見的疾病之一,發生率佔了全球成人的1%,其好發年紀為30到60歲之間,且特別容易發生在男性病患身上,臨床上小孩則較少發生。據統計,超過80%的唾液腺結石發生於下頷腺,6%發生於腮腺,只有2%於舌下腺或其他小唾液腺體。回顧文獻所提及唾液腺結石的大小不一,約90%的病例結石小於1 cm,僅不到8%的病患其結石大於1.5 cm,這些大於1.5 cm的結石則被定義為巨大唾液腺結石。在臨床上,無症狀的巨大唾液腺結石非常罕見,故我們提出此個案報告供經驗分享。此案例為48歲女性,本身無特別過去病史,因喉嚨有異物感1個月來本院門診就診,意外發現左側口底有一顆疑似腫瘤的無壓痛腫塊,經影像學檢查發現,其在下頷腺管有一顆直徑約3 cm大的唾液腺結石阻塞,合併左側唾液腺管擴張及左下頷腺完全萎縮;病患無任何臨床不適及唾液腺結石等病史。最後病患接受了經口唾液腺管取石手術,並完整移除了大小為3.5×1.4 cm的巨大結石,後續病患恢復狀況良好,於術後第4天順利出院,且病患於門診追蹤1年之久,過程並無發現任何復發情形。
Sialolithiasis is one of the most common diseases of salivary glands. More than 80% of the sialoliths occur in the submandibular glands. While most of the calculi are less than 10mm in size, 7.6% are larger than 15mm and are classified as giant sialoliths. We demonstrate a rare case of asymptomatic giant sialolith in the left Wharton's duct with a total atrophy of the left submandibular salivary gland. A 48-year-old female patient presented with lumping sensation for 1 month. A left mouth floor mass was found accidentally during examination and was later revealed to be a painless sialolithiasis. Image study revealed a giant sialolith in the left Wharton's duct with sialectasis and left submandibular gland total atrophy. She underwent transoral sialolithotomy with removal of a huge stone, measuring 3.5×1.4 cm in size. Sialolithiasis usually presents with typical symptoms of the involved salivary gland, and the size of calculi is usually less than 20mm. This is a rare case report of an asymptomatic giant sialolith in the Wharton's duct, causing left submandibular salivary gland total atrophy, and its diagnosis and management.