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Mooren氏潰瘍-病例報告

Mooren's Ulcer-A Case Report

摘要


病人為一位34歲Turner氏症候羣(Syndrome)的女性,同時全身併發高血壓、甲狀腺機能亢進及骨髓灰質炎。其兩眼罹患Mooren氏潰瘍,右眼因周邊角膜潰瘍,後因嚴重細菌感染,已於70年l月將右眼球摘除。左眼於71年2月也因周邊角膜潰瘍而疼痛、畏光,來本院求診。本文報告此病例的詳細臨床變化過程,以及治療情形,並提出討論。

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並列摘要


Mooren's ulcer is a relatively rare but well-known disease of unknown etiology. It begins in the corneal periphery with overhanging edge, and progresses relentlessly first circumferentially then toward the entire cornea. I report a case with bilateral Mooren's ulcer and present the detail clinical course. The patient was a 34-year-old female who was proved to have Turner's syndrome and systemically associated with hyperthyroidism, hypertension and poliomyelitis. Right eye was enucleated 1 year ago because of destructive Mooren's ulcer with secondary infection. She first visited V. G. H. due to pain, redness, photophobia and tearing of the left eye for more than 1 month. Mooren's ulcer was diagnosed and treated with limbal conjunctivectomy for 2 occasions, preserved seleral grafting for 3 occasions and doughnut shaped inlay lamellar keratoplasty. But all failed to alter the progress of the ulcer, and ended with thinned, vascularized, opaque cornea without stromal tissue. In the clinical course, limbal conjunctivectomy had some temporary benefit but frequently was followed by recurrence in this case. The ulcer might also invade the scleral graft and lamellar corneal graft. At the end stage of Mooren's ulcer in such a case, penetrating keratoplasty will be indicated.

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