- 期刊
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Pilocarpine Gel的臨床研究
A Clinical Study of Pilocarpine Gel
摘要
本文報告8位正常人及18位隅角開放性青光眼病人接受4%Pilocarpine gel一天點眼一次的臨床觀察。結果顯示降壓效果在正常人組中至少維持20小時，於隅角開放性青光眼組中，至少維持18小時。Pilocarpine引起的不適症狀及調節性近視，隨著點眼後時間而緩和。為此我們同意Pilocarpine gel可應用在臨床，並應在睡前使用，以減少白天工作的不適，但在使用期間，須個別觀察點眼後之變化，尤其注意點眼後18小時以後的眼壓。
關鍵字
無資料並列摘要
Eight normal persons and eighteen primary open angle glaucoma patients participated in 3 day observation involving a single application of pilocarpine gel. A significant lowering of intraocular pressure was found. The effect occured within 20 hours for normal persons and 18 hours for glaucoma patients. The side effect of pilocarpine gel was clearly noticeable during the first few hours after gel instillation. But it remissed almost completely at 8-10 hours after gel instillation. Therefore, Pilocarpine gel can be endorsed as an effective medication (ie. within 18-20 hours) for the vast majority of patients. However, it is incumbent on the prescribing ophthalmologist to measure the IOP 18-24 hours after pilocarpine gel instillation to ensure adequate control of IOP.