Diamox引起之低鉀血症―病例報告

Diamox-Induced Hypokalemia: Case Report

華國泰(Kuo-Tai Hwa) ； 李世煌(Shi-Huang Lee)

《中華民國眼科醫學會會刊》 26卷1期 (1987/05) Pp. 59-63

https://doi.org/10.30048/ACTASOS.198705.0012

摘要

Diamox臨床上很少產生嚴重的低鉀血症；本病例為一位六十一歲男性病患，口服Diamox治療青光眼，發生嚴重的鉀缺乏與血鉀過低，導致四肢鬆弛性癱瘓，身體極度虛弱，經急救後恢復正常。本文分析血鉀過低的原因並討論治療及預防的方法。

並列摘要

Although there is an initial potassium depletion in patients receiving Diamox (Acetazolamide) therapy, this effect does not appear to be of any clinical significance in long-term therapy if there is an adequate dietary intake of potassium. We report a case of severe hypokalemia caused by decreasing potassium intake (poor food intake) and increasing gastro-intestinal potassium excretion (vomiting) due to Diamox therapy. The patient had flaccid paralysis of extremities, and the muscle strength was grade 2 (movement but not against gravity). The serum potassium was 1.5 mEq/L (Normally, 3.5 to 5.3 mEq/L). EKG revealed S-T segment suppression, T-wave disapperance and prominent U-wave. The patient received treatment with 15% KCI intravenously drip and 10% KCI orally for 5 days. The symptoms subsided, and the serum potassium returned to normal.

並列關鍵字

Diamox ； hypokalemia ； acetazolamide ； carbonic anhydrase inhibitor