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葛瑞夫茲眼症之臨床觀察

Clinical Observation of Graves' Ophthalmopathy

摘要


觀察84例葛端夫茲眼症病患之臨床表徵及實驗室檢查,並報告統計分析結果。症狀以畏光最常見,依次為流淚、眼痛、視力模糊、複視。徵候以眼臉水腫最常見,依次為眼臉退縮、眼窩周圍水腫、視力不良、突眼、外眼肌運動受阻、角膜傷害。表現眼部症狀者,其甲狀腺功能亢進者64%,正常者31%,低下者5%。突眼(≥17mm)者58%;眼臉退縮者85%;外眼肌運動障碍者57%,下直肌受侵犯最常見,內直肌次之。視力0.8以上者69%,0.3以下者17%。眼壓高於22 mmHg者只有8%。眼睛向上凝視之眼壓比正位之眼壓高過3mmHg者佔83%,有統計學意義。男女之比為1比1.4,男性病患比一般報告為多,乃本院作業特殊之故。

關鍵字

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並列摘要


Clinical presentations and laboratory findings in a series of 84 patients with Graves' ophthalmopathy were analyzed. Photophobia was the most common symptom, followed by lacrimation, eye pain, blurred vision, diplopia. Eyelid edema was the most common sign, followed by eyelid retraction, periorbital edema, impaired vision, exophthalmos, limitation of extraocular muscle, corneal lesion. Thyroid function revealed hyperthyroidism in 64% of 84 cases; euthyroid status in 31%, and hypothyroidism in 5%. Eyelid retraction encountered in 85%; exophthalmos in 58%; extraocular muscle limitation in 57%. The inferior rectus muscle was the most common muscle involved. In 83% of eyes examined, the intraocular pressure increased 3mmHg or more in upper gaze than in primary position of eyeball. That was statistically significant.

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