Roth氏斑又稱中心白點網膜出血,為許多全身性疾病的網膜出血特徵。中心白點的病理變化不一,但從外觀上無法鑑別診斷。除了細菌性栓塞、白血病細胞浸潤造成中心白點出血外,網膜出血後的止血過程中可因血小板-纖維蛋白凝集而形成中心白點。本文報告二病例對Roth氏斑的臨床意義,加以討論。
Roth spot was thought as the specific ocular sign which is specific to infectious endocarditis. The pathogenesis of the white center is versatile. In addition to the septic emboli, leukemic cell infilitration which cause the white center; plateletfibrin aggregation after retinal hemorrhage may be the main cause of the white-centered retinal hemorrhage.