從臨床評估Stargardt氏病與黃色斑狀眼底之關係

The Clinical Evaluation of Relationship between Stargardt's Disease and Fundus Flavimaculatus

李家福(Chia-Fwu Lee) ； 丁民峰(Min-Fong Ting) ； 林嘉理(Chia-Lee Lin)

《中華民國眼科醫學會會刊》 30卷2期 (1991/12) Pp. 65-69

https://doi.org/10.30048/ACTASOS.199112.0054

摘要

本文從榮民總醫院視網膜門診中收集了14例的斑點網膜病變之患者，其中8例為Stargardt氏病(Stargardt's disease)，4例為男性，4例為女性；黃色斑狀眼底6例，男性4例，女性2例，其中三例包含了黃斑部的病變。
由年齡的分佈，求診的原因，視力的變化，眼底斑點之位置、形狀和血管螢光攝影的斑點變化，且於追蹤過程中黃斑病灶往外擴展之變化，故推論此兩疾病為一體之兩面。

並列摘要

The term fundus flavimaculatus described by Franceschette in 1963 as the appearance of yellow-white, irregularly shaped flecks in the fundus at the but may be found at the equator. Macular dystrophy was present in 50% of cases.
Stargardt's disease was used by Stargardt in 1909 as a rescessively inherited macular dystrophy. It was noted between ages of 8 and 15 years with decreased visual acuity. In the early stages, the macula is ophthalmoscopically normal. Later, a horizontally oval area of atrophy and pigment dispersed develops.
Fourteen cases of fleck retina were collected since 1978. There were 8 cases of Stargardt's disease, 4 males and 4 females; 6 cases of fundus flavimaculatus, 4 males and 2 females. In fundus flaviculatus, two groups were found that one was macula involved and another one was without macular lesion, 3 cases in each group.
From the distribution of patient age, chief complain on visiting, deterioration of visual acuity, pattern of fleck of retina and phase related chang of fleck in the flurorescin angiography, we suspected these two diseases were caused by the same origin but in different expression.

並列關鍵字

Stargardt's disease ； Fleck ； Fundus Flavimaculatus ； Lipofuscin