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以低張及高張輸液治療玻璃體出血之評估
Evaluate the Effect of Hypotonic and Hypertonic Fluid Infusion Therapy for Vitreous Hemorrhage
摘要
民國80年中華民國眼科醫學會曾有人提出一篇以低張及高張輸液(Hypotonic and hypertonic fluid infusion)治療玻璃體出血之報告，八位病人中有六位視力改善且玻璃體出血有顯著廓清。為進一步探討此方法的效果，我們做了兩個臨床統計： （一）以隨機的方式選擇玻璃體出血的病人作低張及高張輸液治療（以下簡稱輸液治療），以評估其療效。結果發現輸液治療並不能增加玻璃體出血廓清的比率，只能縮短其廓清的時間；且發病一週內就接受此輸液治療者似有較佳療效。 （二）針對糖尿病視網膜病變所引起之玻璃體出血，就其輸液治療之成績和後遺症作獨特的評估與報導。經統計分析結果顯示：輸液治療並不能增加糖尿病視網膜病變之玻璃體出血廓清的比率，亦不能縮短其廓清的時間，且引起較多之併發症。因此，對於糖尿病視網膜病變引起玻璃體出血的病人，我們並不建議其接受輸液治療。
關鍵字
無資料並列摘要
In 1991, there was a report with the topic of ”hepotonic and hypertonic fluid infusion therapy of vitreous hemorrhage” presented in the annual meeting of Ophthalmological Society of the Republic of China. The report stated that 8 patients received fluid infusion therapy and the vitreous hemorrhage was markedly cleared and visual acuity dramatically improved in 6 patients. In order to evaluate the effect of hypotonic and hypertonic fluid infusion therapy, we set up two clinical analyses: (1) We randomly selected 25 patients with vitreous hemorrhage as experimental group to receive fluid therapy, and another 25 patients with vitreous hemorrhage as control group. We analyzed the statistical differences and found that: the long term visual acuity outcome and vitreous hemorrhage clearance percentage was not increased with fluid therapy. Fluid therapy could only shorten the vitreous hemorrhage clearance time and if onset time is less than one week, the result of fluid therapy seemed better. (2) We collected 30 cases of diabetic vitreous hemorrhage as experimental group to receive fluid infusion therapy and 30 cases as control group. After the statistical analysis, we found that there were no statistical differences between, the two groups. Besides, there were some complications after fluid infusion therapy, including: general discomfort, severe vomiting and gastralgia and cerebrovascular accident. So, fluid infusion therapy is not favoured for diabetic vitreous hemorrhage.