- 期刊
- OpenAccess
Flavobacterium Indologenes Keratitis-Case Report
頑抗性黃桿菌角膜潰瘍－病例報告
摘要
黃桿菌(Flavobacteria)是眼睛罕見的致病源，主要分佈於土壤，水源，植物，食物，甚至醫院水源以及潮濕表面。對大多數抗生素具抗藥性，乃其特色。免疫系統不全或長期住院病人可能引起黃桿菌伺機感染。而頑抗性黃桿菌(Flavobacterium indologenes)角膜潰瘍目前文獻上尚無記載。吾人報告一例右眼濺入地下水而導致頑抗性黃桿菌角膜潰瘍之病例，培養出之頑抗性黃桿菌，抗藥性達十三種之多，僅ceftazidime具中等程度的藥物敏感性。對於長期住院或有伺機感染危慮的病人，黃桿菌應列入頑抗性角膜炎之鑑別診斷。Ceftazidime (Fortum)屬於第三代cephalosporin，則提供了治療具多種抗藥性之細菌感染，另一種有效的選擇，在國外已有用於角膜炎的第一線治療。
關鍵字
無資料並列摘要
Flavobacterium indologenes (F. indologenes) has recently been implicated in nosocomial or opportunistic infection, It has been isolated from lids, conjunctiva, and lacrimal system, and is resistant to most antibiotics. No previous cases of F. indologenes keratitis have been reported in the literature. The natural habitat of flavobacteria is soil, water, plants, and foodstuffs. In the hospital environment, these bacteria exist in water systems and wet surfaces. They are not part of the normal ocular flora. Flavobacterium indologenes, (synonymous in the past with F. bastinum, F. gleum, and llb), is strongly pigmented (yellow to orange) and indole positive. Highly notable is the organism's resistance to most antibiotics, It may be sensitive to erythromycin, rifampin, cephaloridine, trimethoprimsulfamethoxazole, and chloramphenicol. Ceftazidime, as a third-generation cephalosporin, has a potent bacteriocidal activity. We present such a case of F. indologenes keratitis with successful treatment with topical ceftazidime.