小兒的固體腫瘤中最常見轉移至眼睛的,是神經母細胞瘤。我們報告一位七歲男孩,其神經母細胞瘤有兩個不常見的臨床表現:眼眶骨的轉移,以及視神經功能的部份回復。病童最初症狀是凸眼和視力模糊,切片和全身檢查確認是第四期神經母細胞瘤。儘早給與有效的多重化學療法,避免造成永久的壓迫性視神經病變。我們強調;對於有任何懷疑眼部轉移的病童,應予以徹底檢查和密切追蹤眼部變化,以維護其視力。
Neuroblastoma is the most common pediatric solid tumor metastatic to the eye. We report a 7-year-old boy of neuroblastoma with two unusual manifestations: bony orbital metastasis and partially reversible optic nerve function. He initially presented with proptosis and blurred vision. Biopsy and systemic surveys confirmed the diagnosis of stage VI neuroblastoma. Early initiation of effective, multiagent chemotherapy prevented permanent compressive optic neuropathy. We recommend that children presenting with any suspected ophthalmic features should undergo thorough investigations and close ophthalmic follow-up to preserve their vision.