- 期刊
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Clinical Experiences in Blepharochalasis Syndrome
眼瞼鬆弛症候群之臨床經驗
摘要
目的：報告眼瞼鬆弛症候群的臨床表徵，鑑別診斷與長期迫蹤治療之結果。 方法：針對2004年至2009年間追蹤的六位眼瞼鬆弛症候群病例進行回溯性研究，探討其好發族群、臨床表現、相關加重因子、病理特徵及治療。 結果：本研究共收集到五位女性及一位男性眼瞼鬆弛症候群之病例，平均發病年齡約十六歲，急性眼皮水腫平均兩天內可恢復，但反覆發作可能因疾病高活動度及病患早年發病而持續數年。所有的病例上眼瞼都受影響，其中兩位較嚴重患者，同側下眼瞼及另一眼上眼瞼亦出現相關皮膚變化。五位病例對於提上瞼肌筋膜復位手術結果感到滿意。 結論：眼瞼鬆弛症候群病患，在急性期容易與過敏性血管水腫混淆且對抗組織膠的反應不佳。對於臨床出現青少年期才開始的眼皮反覆水腫，或後天性眼瞼下垂的年輕病患，應注意是否有眼瞼鬆弛症候群的相關症狀及病徵，並列入鑑別診斷中。
關鍵字
無資料並列摘要
Purpose: To report the clinical manifestations and experiences in blepharochalasis syndrome. Methods: We performed a retrospective, noncomparative chart review on six patients with blepharochalasis syndrome who were followed up at our hospital from 2004 to 2009. The demographics, clinical features, associated factors, clinical courses, differential diagnosis, treatment and histopathological results were discussed. Results: Six patients (5 women, 1 man) with an average presenting age of 16 (range, 10-23 years) had blepharochalasis syndrome. The attack duration averaged 2 days, but the recurrent episodes of eyelid edema sometimes lasted for years. The attack frequency was associated with the stage of the disease and the age of the patients. All patients had upper lid involvement, and lower lid involvement were only found in severe cases. Four patients had unilateral eyelid edema, and the other two had bilateral eyelid edema. Five of the patients received levator aponeurosis advancement surgery, and the postoperative results were satisfactory. Conclusion: We presented our clinical experiences in blepharochalasis syndrome in Taiwan. Because it is easily misdiagnosed as allergic angioedema in the acute stage, recurrent edema beginning in adolescence and a poor response to antihistamines may help to make a differential diagnosis. We should consider the possibility of this rare syndrome when diagnosing young patients having unusual acquired ptosis, with redundant, thinning, atrophic, and stretched eyelid skin.