目的:本文報告二例高三酸甘油脂血症合併罕見脂血性視網膜。方法:案例報告。結果:第一位患者最初以反覆發作之急性胰臟炎合併引起胰島素依賴型糖尿病來表現。第二位患者因第二型糖尿病定期於本院門診追蹤糖尿病視網膜病變。兩位患者皆有增生性糖尿病視網膜病變。眼底檢查可發現兩位患者視網膜血管呈現乳白粉色。並且動靜脈呈現幾乎相同顏色,以至於兩者之差異只剩下管徑大小可以做區分。第一位患者最初血中三酸甘油脂濃度超過7000 mg/dl。治療一週後,三酸甘油脂下降至低於500 mg/dl。第二位患者於發現視網膜異常時,血中三酸甘油脂則是超過4900 mg/dl。三個月後血中三酸甘油脂下降至1102 mg/dl。脂血性視網膜的表現伴隨血中三酸甘油脂的下降而消失。結論:脂血性視網膜是一種與高三酸甘油脂血症成正相關性的獨特表現。
Purpose: To present two rare cases with striking retinal manifestation of hyperlipidemia described as lipemia retinalis. Methods: Case reports. Results: The first case presented with repeated episodes of acute pancreatitis with secondary insulin dependent diabetes mellitus. The second case presented with type II diabetes mellitus. Both cases were referred to us for survey of diabetic retinopathy, for which proliferative stage was found. More remarkably, the retinal vessels appeared creamy salmon pink. The arteries and veins seem nearly indistinguishable other than the larger caliber of the latter. In our first case, her triglyceride concentration exceeded 7000 mg/dl at presentation. One week after treatment, laboratory testing showed reduced triglyceride to below 500 mg/dl. In the second case, her triglyceride concentration was over 4900 mg/dl at the first sign of lipmeia retinalis. At the three-month follow up, her triglyceride level had lowered to just over 1000 mg/dl. The findings of lipemia retinalis disappeared along with reduction of serum triglyceride in both cases. Conclusion: Lipemia retinalis is a specific finding thought to be directly correlated with elevated serum triglyceride level.