- 期刊
The Non-Host Selective Toxin Cercosporin Produced by Cercospora Species
縱談尾孢真菌（Cercospora）產生的植物毒素Cercosporin
摘要
尾孢真菌（Cercospora）產生光啟動的植物毒素，稱之為cercosporin，其可破壞植物細胞膜並誘導營養素的流漏。尾孢病原眞菌可以感染並侵害衆多的植物種類，並且造成經濟損失。這種病原眞菌之所以有如此廣泛的寄主，乃因為cercosporin產生的單型氧及超氧分子（superoxide）對所有的細胞都具有普遍的毒性。因此，想利用遺傳育種的方法來培育抗尾孢真菌或cercosporin 毒素植物品種，是極為困難的。Cercosporin 毒素是尾孢病原真菌侵染寄主植物時重要的毒力因子之一。因此，進一步了解其在病勢發生時所扮演的功能以及其生合成、調控的機制，也許未來可發展有效的防治策略，例如，篩選可以抑制cercosporin 生合成必需的基因或蛋白的藥劑，進而減輕尾孢病原眞菌所造成的為害。
並列摘要
The photoactivated cercosporin toxin produced by Cercospora species causes damage to plant cell membranes and induces leakage of nutrients. Cercosporin is toxic because of production of 1O_2 that has universal toxicity to many cells. Cercospora species can infect numerous plant species and cause major economic problems. Cercosporin has general toxicity to many host plants due to its ability to generate singlet oxygen and superoxide. It is extremely difficult to develop breeding systems for resistance to Cercospora fungi or to cercosporin toxin. Cercosporin is an important factor for fungal virulence in Cercospora species. Understanding the role of cercosporin in disease progress, and cercosporin's biosynthesis pathway and regulation mechanisms may have potential in developing new strategies for disease management by targeting cercosporin biosynthetic genes or proteins in the future.