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A Solitary Sternal Metastasis Mimicking Physiological Uptake of Synchondrosis Sternalis in a Breast Cancer Patient: Case Report and Literature Review

乳癌單一胸骨轉移疑似生理性胸骨軟骨聯合攝取

摘要


乳癌病人出現單一性胸骨轉移與預後關係重大,此一骨掃描發現時與生理性胸骨軟骨聯合攝取易被忽視。吾等報告一位54歲初診斷為左側乳癌患者於一年前即出現胸痛,經轉介接受骨掃描發現:在胸骨軟骨聯合處有不均勻攝取現象而疑似生理性胸骨軟骨聯合攝取;但由病史及骨掃描局部放大影像則更清楚發現此一不均勻攝取呈現嗜骨與成骨性異常,進一步生化、理學檢查及電腦斷層影像證實此異常為一單一性胸骨轉移病灶。

並列摘要


A solitary sternal uptake is critical for prognosis in patients with breast cancer. We describe a case of breast cancer involving synchondrosis sternalis presented as a solitary uptake mimicking physiological uptake. A 54-year-old woman with a history of left breast cancer and chest pain 1 year ago was referred for screening of metastatic disease. Tc-99m MDP bone scan revealed a heterogeneous uptake around synchondrosis sternalis mimicking a physiological uptake. The magnified view favored a metastatic lesion based on lytic and blastic uptake pattern combined with a history of breast cancer. A subsequent biochemical, physical examinations and chest CT depicted it as a solitary osteolytic sterna metastasis.

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