- 期刊
Chronic Pancreatitis with Brunner's Gland Hyperplasia of Ampulla Vater and Duodenal Obstruction
慢性胰臟炎併十二指腸壺腹Brunner氏腺體增生及十二指腸阻塞：病例報告
摘要
Brunner氏腺體主要生長於幽門與十二指腸壺腹之間，大多數Brunner氏腺體產生的腫瘤大多數無症狀，或僅輕微出血，至於造成胰臟炎與腸阻塞實屬罕見。本文報告一例33歲男性反覆上腹痛與胰臟炎發作，經檢查為十二指腸壺腹處腫瘤造成腸阻塞及胰頭處胰臟炎，藉由十二指腸胰頭切除後治癒。病理證實為十二指腸壺腹處Brunner氏腺體增生造成腸阻塞與胰頭腺體破壞。查閱文獻記載，類似案例僅有少數，手術方式以症狀治療為主，本案例則藉以Whipple氏手術處理十二指腸壺腹處阻塞及胰頭處胰臟炎。僅以此案例，作相關文獻分析與討論。
並列摘要
Hyperplasia or tumors of Brunner's glands in the duodenum are rare and many of them have been incidental findings. The most common symptom was hemorrhage. Duodenal obstruction and its resulting pancreatitis are extremely rare. Herein, we reported a 33-year-old male alcoholic presented with recurrent chronic pancreatitis and progression of bowel obstruction. Image and clinical surveillance revealed duodenal obstruction at the level around the Ampulla Vater. Although biopsy did not yield malignancy, he underwent the Whipple operation with uneventful course and the patient resumed active work 2 months after the operation. The pathologic test results showed Brunner's gland hyperplasia at the Ampulla Vater with destruction of the pancreatic duct.