輸血相關循環超載可能是最難辨識的危及生命的輸血併發症。開始輸血後的數分鐘或數小時內,患者呈現呼吸窘迫而且可能出現以下的臨床症狀:端坐呼吸、發紺、心跳上升、高血壓。典型的特徵是血壓上升、心跳加快及肺微血管楔狀壓力增加。輸血相關循環超載的治療包括立即停止進行中的輸血;臨床症狀通常因利尿劑的給予及通氣的支持而改善。
Transfusion-associated circulatory overload (TACO) may be the most under-recognized and life-threatening transfusion complication. During or within minutes to hours of transfusion, patients develop respiratory distress, and may develop orthopnea, cyanosis, tachycardia, and hypertension. Elevated blood pressure, tachycardia, and increased pulmonary wedge pressure are the typical stigmata. Treatment of TACO starts with discontinuing any ongoing transfusion and TACO usually responds to diuresis and ventilatory support.