- 期刊
百合(Lilium lancifolium Thunb.)萃取物對大鼠氧化壓力之影響
Effect of Lilii Bulbus Extract Feeding on the Antioxidant System in Rats
摘要
Lily bulb is a traditional medicine and health food in China. The purpose of this study was to examine the antioxidant ability of lily extract in vitro and in vivo. First, the DPPH scavenging effect was conducted to measure the antioxidant ability in vitro. Then, 32 male weaning rats were devideded into four groups according to the following diets: a control diet, or 0.2%, 1%, 5% lily extract-containing diets (C, L, M, and H, respectively). The feeding period was 30 days. The DPPH scavenging effect increased as the concentration of lily extract increased. There were no significant difference in final body weight, feed efficiency and plasma total antioxidant status (Trolox Equivalent) among the four groups. The levels of thiobarbituric acid-reactive substances (TBARS), reduced glutathione in the liver also showed no significant difference among the four groups. However, the activities of hepatic glutathione peroxidase (GPx) were significantly higher in M group when compared with C group (p＜0.05). In conclusion, the lily extract showed free radical scarvenging effect in vitro. The moderate percentage of lily extract in diet could enhance the enzyme activities of GPx in rat liver.
並列摘要
Lily bulb is a traditional medicine and health food in China. The purpose of this study was to examine the antioxidant ability of lily extract in vitro and in vivo. First, the DPPH scavenging effect was conducted to measure the antioxidant ability in vitro. Then, 32 male weaning rats were devideded into four groups according to the following diets: a control diet, or 0.2%, 1%, 5% lily extract-containing diets (C, L, M, and H, respectively). The feeding period was 30 days. The DPPH scavenging effect increased as the concentration of lily extract increased. There were no significant difference in final body weight, feed efficiency and plasma total antioxidant status (Trolox Equivalent) among the four groups. The levels of thiobarbituric acid-reactive substances (TBARS), reduced glutathione in the liver also showed no significant difference among the four groups. However, the activities of hepatic glutathione peroxidase (GPx) were significantly higher in M group when compared with C group (p＜0.05). In conclusion, the lily extract showed free radical scarvenging effect in vitro. The moderate percentage of lily extract in diet could enhance the enzyme activities of GPx in rat liver.