Desquamative Interstitial Pneumonitis-A Case Report and Literature Review

脫屑性間質性肺炎－病例報告及文獻回顧

蘇麗慧(Li-Hui Soh) ； 蔡鎮良(Cheng-Liang Tsai) ； 彭忠衎(Chung-Kan Peng) ； 賴傳才(Chuan-Tsai Lai) ； 彭萬誠(Wann-Cherng Perng) ； 吳清平(Chin-Pyng Wu) ； 顏鴻欽(Horng-Chin Yan)

《胸腔醫學》 19卷2期 (2004/04) Pp. 132-138

https://doi.org/10.29806/TM.200404.0008

摘要

脫屑性間質性肺炎(Desquamative interstitial pneumontis)是一種在組織病理學上呈現肺泡填充巨噬細胞且沒有明顯纖維化的間質性肺病。它與抽煙息息相關，且對皮質類固醇治療反應良好。在此我們報告一位醫源性庫辛氏症候群病患臨床表現以漸進性氣促及雙側瀰漫毛玻璃狀肺浸潤的胸部X光表徵，進而以胸腔內視鏡肺切片證實為脫屑性間質性肺炎。此病患對皮質類固醇治療反應良好。此病患之脫屑性間質性肺炎可能起因於抽煙及皮質類固醇的突然終止治療有關。

關鍵字

脫屑性間質性肺炎 ； 間質性肺病

並列摘要

Desquamative interstitial pneumonitis (DIP) is a subgroup of interstitial lung disease that has a distinctive histopathology, with macrophages filling the alveolar spaces and no significant fibrosis. DIP has a strong association with cigarette smoking, and a better prognosis and response to corticosteroid. We report a patient with introgenic Cushing's syndrome who presented with progressive dyspnea and a bilateral diffuse ground-glass pattern on the chest roentgenograph, and who was diagnosed with DIP after video-assisted thoracoscopic (VATS) lung biopsy. Her condition was uneventful after treatment with corticosteroid. The development of DIP in this case may be associated with cigarette smoking and the abrupt discontinuation of the corticosteroid.

並列關鍵字

DIP ； desquamative interstitial pneumonitis ； ILD ； interstitial lung disease