- 期刊
Pulmonary Mucormycosis Successfully Treated by Resection-A Case Report and Review of the Literature
僅以肺葉切除的方式來治癒肺部白黴菌症－病例報告
摘要
白黴菌的感染，十分少見，但對於免疫力不好的病患確是相當重要且嚴重。如糖尿病，血液腫瘤疾病，慢性腎衰竭，長期使用類固醇或免疫抑制劑，以及骨髓移植。白黴菌為腐生性，不分隔且分支的菌絲，常見的感染部位為鼻腦部，肺部；肺部的感染為次多。其死亡率很高。因此，早期正確地診斷與積極治療（包括控制其本身疾病，並以外科方式切除感染部位和合併使用抗黴菌的藥物），對於預後有正面的幫助；其中早期正確地診斷與積極以外科方式切除感染部位為最重要。是否須使用抗黴菌的藥物可由感染的程度與其本身疾病來決定。 我們提這個案例，僅以肺葉切除的方式來治癒肺部白黴菌的感染而無使用抗黴菌的藥物。
並列摘要
Pulmonary mucormycosis is a rare, but serious, opportunistic fungal infection in immunocompromised persons. It is caused by saprophytic non-septated branching hyphae of the order Mucoralis. The mortality rate is high. The successful treatment of mucormycosisis is based on 4 principles: early diagnosis, control of the underlying disease, aggressive, extensive surgical intervention of the infectious focus with necrotic tissue, and medial treatment with antimycotic agents. Early diagnosis and surgical treatment has a high impact on the outcome of mucormycosis. Surgical resection in localized disease remains the treatment of choice, except for cases with hematological disease and neutropenia. Whether or not to use antimycotic agents may be decided based on the extent of fungal infection and the underlying disease. This report concerns a case of pulmonary mucormycosis in a patient with type Ⅱ diabetes who was successfully treated with pulmonary resection without amphotericin B therapy.