Pulmonary Blastoma-A Case Report and Review of the Literature

肺胚胎瘤－病例報告及文獻回顧

楊家燊(Chia-Shen Yang) ； 郭光泰(Kuang-Tai Kuo) ； 周德盈(Teh-Ying Chou) ； 王良順(Liang-Shun Wang)

《胸腔醫學》 20卷5期 (2005/10) Pp. 478-483

https://doi.org/10.29806/TM.200510.0017

摘要

肺胚胎瘤是一種相當罕見的肺部惡性腫瘤，約佔原發性肺癌的 0.25-0.5%，組織學上它是一種不成熟、初級的表皮及實質細胞的組合，與胚胎期的肺類似，它們的行為像非小細胞癌，年齡屬的分佈由新生到80歲均可發生。預後非常的差，五年的存活率只有15%。我們報告一位七十歲男性病患，他的症狀為咳嗽、喘及體重減輕。入院前六個月接受過心臟繞道手術，當時的胸部X光並無異狀，而入院時的胸部X光發現右下葉有一巨大腫瘤，後行右下肺葉切除，病理報告是典型性的肺胚胎瘤，而無淋巴結的轉移。我們回顧文獻，得知此種腫瘤雖然增生很快，但可經由外科手術完全切除。

關鍵字

肺胚胎瘤 ； 肺葉切除

並列摘要

Pulmonary blastomas are a group of rare malignant neoplasms and account for only 0.25-0.5% of primary malignant lung tumors. Histologically, they contain a mixture of immature or primitive epithelial and mesenchymal components, resembling embryonal lungs. They behave like non-small cell lung carcinomas (NSCLC), and the age distribution of patients with these tumors ranges from newborn to 80 years. The prognosis is rather poor and the 5-year survival is around 15%. Herein, we report a case of pulmonary blastoma presenting with productive cough, exertional dyspnea, and evident body weight loss. The chest radiograph taken 6 months earlier revealed no remarkable finding, but 1 taken prior to admission showed a huge mass in the right lower lung field. A right lower lobe (RLL) lobectomy was performed, and the pathology report showed a classic biphasic pulmonary blastoma without lymph node metastasis. The literature is reviewed, and we concluded that complete resection can be achieved despite the tumor's rapid growth rate.

並列關鍵字

pulmonary blastoma ； lobectomy