原發性肺腺癌轉移至乳房是極為罕見的。我們報告一個26歲的女性,在評估其轉移性腦瘤病灶時,意外發現乳腺結節。在進行了超音波導引下乳腺結節細針穿刺細胞學檢查和電腦斷層導引下肺部腫塊穿刺活檢之後,細胞本身的形態學特徵和對甲狀腺轉錄因子-1的陽性免疫反應證實了原發性肺腺癌合併乳房轉移之診斷。該病人正接受適當治療且其臨床情況逐漸改善。因為原發性及轉移性乳腺癌的治療方法及預後非常不同,所以,準確的將兩者加以區分是十分重要的。
Metastatic breast adenocarcinoma of pulmonary origin is extremely rare. Herein, we present an incidental finding of mammary nodules in a 26-year-old female during the work-up for metastatic brain tumors. Sono-guided fine-needle aspiration cytology of the breast nodules and CT-guided needle biopsy of the pulmonary mass were performed. The morphologic features and immunoreactivity to thyroid transcription factor-1 (TTF-1) confirmed this diagnosis. The patient received treatment and the clinical condition improved gradually. It is crucial to accurately distinguish primary breast cancer from a metastasized cancer because both the treatment and the outcome will differ.