- 期刊
Treating Early-Stage Lung Cancer with Radiofrequency Ablation-A Case Report
使用射頻燒灼術（Radiofrequency ablation）治療早期肺癌－一病例報告
摘要
肺癌在台灣的盛行率一直很高。針對早期肺癌的病人，施行手術才有治癒的可能。臨床上因為年紀大、心肺功能差、其他嚴重合併症等，並不是所有早期肺癌的病人都適合接受手術。射頻燒灼術（Radiofrequency ablation, RFA）開始用來治療肝癌，近年來應用在肺部腫瘤的局部控制上，也有預後甚好的結果。我們報告一例老年糖尿病肺功能不佳之早期肺腺癌病人，經過RFA治療且追蹤一年後的臨床經驗，同時回顧目前對於RFA的資訊。RFA的侵襲性小，對病人的肺功能影響不大，可以重複施行，且相關的併發症多在可處理的範圍內。影響治療效果最大的因素就是腫瘤的大小，小於三公分的腫瘤治療效果好。治療後的評估多以電腦斷層及正子攝影當作追蹤的工具。
並列摘要
The prevalence of lung cancer is high in Taiwan. For patients with early-stage lung cancer, surgical resection is the standard treatment. In clinical practice, some patients are poor surgical candidates because of old-age, poor cardiopulmonary functional reserve or other comorbid diseases. Radiofrequency ablation (RFA) has been used to treat hepatocellular carcinoma for a decade with good results, and recently, it has been utilized for local control of lung cancers. We report an elderly patient with early-stage adenocarcinoma of the lung. Her comorbid conditions of diabetes mellitus, rheumatoid arthritis and poor cardiopulmonary function made the risk of surgery high and unacceptable. The patient was treated with RFA and was followed up for 1 year with a good response. RFA-related complications such as pneumothorax, hemoptysis, pain and pleural effusion are readily handled clinically. The efficiency of RFA depends on tumor size. A tumor diameter of less than 3 cm yields good local control. Computed tomography and positron emission tomography are usually used to evaluate the treatment outcome. RFA is a minimally invasive treatment, and preserves the patient's pulmonary function. Repeat treatments are also possible.