Pulmonary truncal fistula is a rare occurrence, and may remain asymptomatic unless the pneumatic fistula progresses to a pneumatocele that can be identified easily. We report a case in which a patient who had previously undergone Port-A-Cath implantation via the right subclavian route developed a pulmonary truncal fistula that presented with a cervical pneumatocele caused by extravasation of the chemotoxic agent from the catheter. This case was successfully managed with thoracoscopic pulmonary fistulectomy with neck debridement.