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Positive Correlation between Pendelluft and Breathing Effort in a Case of Severe Acute Respiratory Distress Syndrome

摘要


Sedation and paralysis are often required for patients with moderate to severe acute respiratory distress syndrome. Daily interruption of sedation and paralysis is a standard of care in the current concept. However, physicians may be concerned that the excessive breathing effort generated by the patients themselves following discontinuation of a muscle relaxant could be harmful. The phenomenon of pendelluft is hypothesized to be associated with such hazards, but the association of pendelluft and breathing effort has not been well established. Here, we report a patient with severe acute respiratory distress syndrome who underwent an electrical impedance tomography recording with simultaneous esophageal manometry monitoring during daily interruption of sedation and paralysis. A positive correlation between the volume of pendelluft, the global inhomogeneity index and breathing effort was noted.

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