- 期刊
Clinical Weaning Factors for Prolonged Mechanical Ventilation Patients: A Retrospective Study in Central Taiwan
摘要
Introduction: Mechanical ventilation is the most commonly used short-term life support technique in the world. But, about 5-10% of mechanical ventilation patients will progress from acute to chronic critical illness and require prolonged mechanical ventilation (PMV). Only 50% of these PMV patients are successfully liberated from mechanical ventilation. Therefore, improving the successful weaning rate and determining the influencing factors are important issues. This study aimed to analyze the factors for successful weaning of respiratory care center (RCC) patients and to determine the important weaning factors in PMV patients. Methods: This was a single-center, retrospective study with 65 patients. This study collected and analyzed patients over the age of 20 in the RCC from October 2019 to August 2020. Results: We found that patients who were successfully weaned from the ventilator had higher Glasgow Coma Scale (GCS) scores, and higher free thyroid (free T4), albumin and calcium levels on admission. In addition, they had lower APACHE II scores, C-reactive protein (CRP), and aspartate aminotransferase on admission. The patients also had higher systolic blood pressure before extubation, higher arterial carbon dioxide partial pressure (PaCO_2) after extubation, and high average albumin and average prealbumin values at the RCC. Conclusion: We found that APACHE II scores, GCS scores, albumin, calcium, CRP, free T4, GOT are important weaning factors for patients admitted to the RCC. Systolic blood pressure and PaCO_2 are important influencing factors before and after the patient is released from the ventilator. In addition to this, average albumin and prealbumin are important weaning maintenance factors when PMV patients are in the RCC.